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SIRT7 antagonizes human stem cell aging as a heterochromatin stabilizer

SIRT7, a sirtuin family member implicated in aging and disease, is a regulator of metabolism and stress responses. It remains elusive how human somatic stem cell populations might be impacted by SIRT7. Here, we found that SIRT7 expression declines during human mesenchymal stem cell (hMSC) aging and...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Protein Cell
Päätekijät: Bi, Shijia, Liu, Zunpeng, Wu, Zeming, Wang, Zehua, Liu, Xiaoqian, Wang, Si, Ren, Jie, Yao, Yan, Zhang, Weiqi, Song, Moshi, Liu, Guang-Hui, Qu, Jing
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Higher Education Press 2020
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7305295/
https://ncbi.nlm.nih.gov/pubmed/32504224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-020-00728-4
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