SIRT7 antagonizes human stem cell aging as a heterochromatin stabilizer

SIRT7, a sirtuin family member implicated in aging and disease, is a regulator of metabolism and stress responses. It remains elusive how human somatic stem cell populations might be impacted by SIRT7. Here, we found that SIRT7 expression declines during human mesenchymal stem cell (hMSC) aging and...

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Bibliografiske detaljer
Udgivet i:Protein Cell
Main Authors: Bi, Shijia, Liu, Zunpeng, Wu, Zeming, Wang, Zehua, Liu, Xiaoqian, Wang, Si, Ren, Jie, Yao, Yan, Zhang, Weiqi, Song, Moshi, Liu, Guang-Hui, Qu, Jing
Format: Artigo
Sprog:Inglês
Udgivet: Higher Education Press 2020
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7305295/
https://ncbi.nlm.nih.gov/pubmed/32504224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-020-00728-4
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