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DNA polymerase D temporarily connects primase to the CMG-like helicase before interacting with proliferating cell nuclear antigen
The eukaryotic replisome is comprised of three family-B DNA polymerases (Polα, δ and ϵ). Polα forms a stable complex with primase to synthesize short RNA-DNA primers, which are subsequently elongated by Polδ and Polϵ in concert with proliferating cell nuclear antigen (PCNA). In some species of archa...
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| Publicat a: | Nucleic Acids Res |
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| Autors principals: | , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2021
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8096248/ https://ncbi.nlm.nih.gov/pubmed/33849056 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkab243 |
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