Novel dopamine receptor 3 antagonists inhibit the growth of primary and temozolomide resistant glioblastoma cells

Treatment for the lethal primary adult brain tumor glioblastoma (GBM) includes the chemotherapy temozolomide (TMZ), but TMZ resistance is common and correlates with promoter methylation of the DNA repair enzyme O-6-methylguanine-DNA methyltransferase (MGMT). To improve treatment of GBMs, including t...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:PLoS One
Huvudupphovsmän: Williford, Sarah E., Libby, Catherine J., Ayokanmbi, Adetokunbo, Otamias, Arphaxad, Gordillo, Juan J., Gordon, Emily R., Cooper, Sara J., Redmann, Matthew, Li, Yanjie, Griguer, Corinne, Zhang, Jianhua, Napierala, Marek, Ananthan, Subramaniam, Hjelmeland, Anita B.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2021
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC8096095/
https://ncbi.nlm.nih.gov/pubmed/33945569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0250649
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk