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Amyloid β‐Peptide(1‐42) Contributes to the Oxidative Stress and Neurodegeneration Found in Alzheimer Disease Brain

Oxidative stress is extensive in Alzheimer disease (AD) brain. Amyloid β‐peptide (1–42) has been shown to induce oxidative stress and neurotoxicity in vitro and in vivo. Genetic mutations that result in increased production of Aβ(1–42) from amyloid precursor protein are associated with an early onse...

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Foilsithe in:Brain Pathol
Main Authors: Butterfield, D. Allan, Boyd‐Kimball, Debra
Formáid: Artigo
Teanga:Inglês
Foilsithe: Blackwell Publishing Ltd 2006
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8096022/
https://ncbi.nlm.nih.gov/pubmed/15605990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1750-3639.2004.tb00087.x
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