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The Amyloid Paradox: Amyloid‐β‐Metal Complexes can be Neurotoxic and Neuroprotective
Senile plaques in the brains of people with Alzheimer disease (AD) are primarily composed of the amyloid‐β (Aβ) peptide and contain substantially elevated levels of iron, copper and zinc. These metals bind to Aβ and have been reported to increase the toxicity of Aβ to cultured neurones. Other report...
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| Pubblicato in: | Brain Pathol |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Blackwell Publishing Ltd
2006
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8095825/ https://ncbi.nlm.nih.gov/pubmed/15605992 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1750-3639.2004.tb00089.x |
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