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Amyloid β‐Peptide(1‐42) Contributes to the Oxidative Stress and Neurodegeneration Found in Alzheimer Disease Brain

Oxidative stress is extensive in Alzheimer disease (AD) brain. Amyloid β‐peptide (1–42) has been shown to induce oxidative stress and neurotoxicity in vitro and in vivo. Genetic mutations that result in increased production of Aβ(1–42) from amyloid precursor protein are associated with an early onse...

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Detalhes bibliográficos
Publicado no:Brain Pathol
Main Authors: Butterfield, D. Allan, Boyd‐Kimball, Debra
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8096022/
https://ncbi.nlm.nih.gov/pubmed/15605990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1750-3639.2004.tb00087.x
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