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A 40‐cM Region on Chromosome 14 Plays a Critical Role in the Development of Virus Persistence, Demyelination, Brain Pathology and Neurologic Deficits in a Murine Viral Model of Multiple Sclerosis

Theiler's virus persists and induces immunemediated demyelination in susceptible mice and serves as a model of multiple sclerosis. Previously, we identified 4 markers–D14Mit54, D14Mit60, D14Mit61, and D14Mit90–in a 40‐cM region of chromosome 14 that are associated with demyelination in a cross...

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發表在:Brain Pathol
Main Authors: Nakane, Shunya, Zoecklein, Laurie J., Gamez, Jeffrey D., Papke, Louisa M., Pavelko, Kevin D., Bureau, Jean‐François, Brahic, Michel, Pease, Larry R., Rodriguez, Moses
格式: Artigo
語言:Inglês
出版: Blackwell Publishing Ltd 2006
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC8095950/
https://ncbi.nlm.nih.gov/pubmed/14655757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1750-3639.2003.tb00482.x
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