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Intracellular and Extracellular Aβ, a Tale of Two Neuropathologies
The central pathological cause of Alzheimer disease (AD) is hypothesized to be an excess of β‐amyloid (Aβ) which accumulates into toxic fibrillar deposits within extracellular areas of the brain. These deposits disrupt neural and synaptic function and ultimately lead to neuronal degeneration and dem...
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| Udgivet i: | Brain Pathol |
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| Hovedforfatter: | |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Blackwell Publishing Ltd
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8095923/ https://ncbi.nlm.nih.gov/pubmed/15779238 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1750-3639.2005.tb00101.x |
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