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Intracellular and Extracellular Aβ, a Tale of Two Neuropathologies

The central pathological cause of Alzheimer disease (AD) is hypothesized to be an excess of β‐amyloid (Aβ) which accumulates into toxic fibrillar deposits within extracellular areas of the brain. These deposits disrupt neural and synaptic function and ultimately lead to neuronal degeneration and dem...

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Podrobná bibliografie
Vydáno v:Brain Pathol
Hlavní autor: Cuello, A. Claudio
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Publishing Ltd 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8095923/
https://ncbi.nlm.nih.gov/pubmed/15779238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1750-3639.2005.tb00101.x
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