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Hypoxia-Responsive, Polymeric Nanocarriers for Targeted Drug Delivery to Estrogen Receptor-Positive Breast Cancer Cell Spheroids

Uncontrolled cell growth, division, and lack of enough blood supply causes low oxygen content or hypoxia in cancerous tumor microenvironments. 17β-Estradiol (E(2)), an estrogen receptor (ER) ligand, can be incorporated on the surface of nanocarriers for targeted drug delivery to breast cancer cells...

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Enregistré dans:
Détails bibliographiques
Publié dans:Mol Pharm
Auteurs principaux: Mamnoon, Babak, Feng, Li, Froberg, Jamie, Choi, Yongki, Venkatachalem, Sathish, Mallik, Sanku
Format: Artigo
Langue:Inglês
Publié: 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8095663/
https://ncbi.nlm.nih.gov/pubmed/32926627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.molpharmaceut.0c00754
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