Targeted polymeric nanoparticles for drug delivery to hypoxic, triple-negative breast tumors

High recurrence and metastasis to vital organs are the major characteristics of triple-negative breast cancer (TNBC). Low vascular oxygen tension promotes resistance to chemo- and radiation therapy. Neuropilin-1 (NRP-1) receptor is highly expressed on TNBC cells. The tumor-penetrating iRGD peptide i...

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Bibliografiska uppgifter
I publikationen:ACS Appl Bio Mater
Huvudupphovsmän: Mamnoon, Babak, Loganathan, Jagadish, Confeld, Matthew I., De Fonseka, Nimesha, Feng, Li, Froberg, Jamie, Choi, Yongki, Tuvin, Daniel M., Sathish, Venkatachalem, Mallik, Sanku
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2020
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC8096163/
https://ncbi.nlm.nih.gov/pubmed/33954285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsabm.0c01336
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