Longitudinal analysis shows durable and broad immune memory after SARS-CoV-2 infection with persisting antibody responses and memory B and T cells

Ending the COVID-19 pandemic will require long-lived immunity to SARS-CoV-2. Here, we evaluate 254 COVID-19 patients longitudinally up to eight months and find durable broad-based immune responses. SARS-CoV-2 spike binding and neutralizing antibodies exhibit a bi-phasic decay with an extended half-l...

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Xehetasun bibliografikoak
Argitaratua izan da:medRxiv
Egile Nagusiak: Cohen, Kristen W., Linderman, Susanne L., Moodie, Zoe, Czartoski, Julie, Lai, Lilin, Mantus, Grace, Norwood, Carson, Nyhoff, Lindsay E., Edara, Venkata Viswanadh, Floyd, Katharine, De Rosa, Stephen C., Ahmed, Hasan, Whaley, Rachael, Patel, Shivan N., Prigmore, Brittany, Lemos, Maria P., Davis, Carl W., Furth, Sarah, O’Keefe, James, Gharpure, Mohini P., Gunisetty, Sivaram, Stephens, Kathy A., Antia, Rustom, Zarnitsyna, Veronika I., Stephens, David S., Edupuganti, Srilatha, Rouphael, Nadine, Anderson, Evan J., Mehta, Aneesh K., Wrammert, Jens, Suthar, Mehul S., Ahmed, Rafi, McElrath, M. Juliana
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Cold Spring Harbor Laboratory 2021
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC8095229/
https://ncbi.nlm.nih.gov/pubmed/33948610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2021.04.19.21255739
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