Reduced binding and neutralization of infection- and vaccine-induced antibodies to the B.1.351 (South African) SARS-CoV-2 variant

The emergence of SARS-CoV-2 variants with mutations in the spike protein is raising concerns about the efficacy of infection- or vaccine-induced antibodies to neutralize these variants. We compared antibody binding and live virus neutralization of sera from naturally infected and spike mRNA vaccinat...

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Publicado no:bioRxiv
Main Authors: Edara, Venkata Viswanadh, Norwood, Carson, Floyd, Katharine, Lai, Lilin, Davis-Gardner, Meredith E., Hudson, William H., Mantus, Grace, Nyhoff, Lindsay E., Adelman, Max W., Fineman, Rebecca, Patel, Shivan, Byram, Rebecca, Gomes, Dumingu Nipuni, Michael, Garett, Abdullahi, Hayatu, Beydoun, Nour, Panganiban, Bernadine, McNair, Nina, Hellmeister, Kieffer, Pitts, Jamila, Winters, Joy, Kleinhenz, Jennifer, Usher, Jacob, O’Keefe, James B., Piantadosi, Anne, Waggoner, Jesse J., Babiker, Ahmed, Stephens, David S., Anderson, Evan J., Edupuganti, Srilatha, Rouphael, Nadine, Ahmed, Rafi, Wrammert, Jens, Suthar, Mehul S.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7924283/
https://ncbi.nlm.nih.gov/pubmed/33655254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2021.02.20.432046
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