Longitudinal analysis shows durable and broad immune memory after SARS-CoV-2 infection with persisting antibody responses and memory B and T cells

Ending the COVID-19 pandemic will require long-lived immunity to SARS-CoV-2. Here, we evaluate 254 COVID-19 patients longitudinally up to eight months and find durable broad-based immune responses. SARS-CoV-2 spike binding and neutralizing antibodies exhibit a bi-phasic decay with an extended half-l...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:medRxiv
Auteurs principaux: Cohen, Kristen W., Linderman, Susanne L., Moodie, Zoe, Czartoski, Julie, Lai, Lilin, Mantus, Grace, Norwood, Carson, Nyhoff, Lindsay E., Edara, Venkata Viswanadh, Floyd, Katharine, De Rosa, Stephen C., Ahmed, Hasan, Whaley, Rachael, Patel, Shivan N., Prigmore, Brittany, Lemos, Maria P., Davis, Carl W., Furth, Sarah, O’Keefe, James, Gharpure, Mohini P., Gunisetty, Sivaram, Stephens, Kathy A., Antia, Rustom, Zarnitsyna, Veronika I., Stephens, David S., Edupuganti, Srilatha, Rouphael, Nadine, Anderson, Evan J., Mehta, Aneesh K., Wrammert, Jens, Suthar, Mehul S., Ahmed, Rafi, McElrath, M. Juliana
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory 2021
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8095229/
https://ncbi.nlm.nih.gov/pubmed/33948610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2021.04.19.21255739
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires