Prophylactic protection against respiratory viruses conferred by a prototype live attenuated influenza virus vaccine

The influenza A non-structural protein 1 (NS1) is known for its ability to hinder the synthesis of type I interferon (IFN) during viral infection. Influenza viruses lacking NS1 (ΔNS1) are under clinical development as live attenuated human influenza virus vaccines and induce potent influenza virus-s...

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Enregistré dans:
Détails bibliographiques
Publié dans:bioRxiv
Auteurs principaux: Rathnasinghe, Raveen, Salvatore, Mirella, Zheng, Hongyong, Jangra, Sonia, Kehrer, Thomas, Mena, Ignacio, Schotsaert, Michael, Muster, Thomas, Palese, Peter, García-Sastre, Adolfo
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory 2021
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8095196/
https://ncbi.nlm.nih.gov/pubmed/33948589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2021.04.28.441797
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