Effects of Influenza A Virus NS1 Protein on Protein Expression: the NS1 Protein Enhances Translation and Is Not Required for Shutoff of Host Protein Synthesis

The influenza A virus NS1 protein, a virus-encoded alpha/beta interferon (IFN-α/β) antagonist, appears to be a key regulator of protein expression in infected cells. We now show that NS1 protein expression results in enhancement of reporter gene activity from transfected plasmids. This effect appear...

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Main Authors: Salvatore, Mirella, Basler, Christopher F., Parisien, Jean-Patrick, Horvath, Curt M., Bourmakina, Svetlana, Zheng, Hongyong, Muster, Thomas, Palese, Peter, García-Sastre, Adolfo
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2002
Fag:
Virus-Cell Interactions
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC135795/
https://ncbi.nlm.nih.gov/pubmed/11773396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.3.1206-1212.2002
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