Effects of Influenza A Virus NS1 Protein on Protein Expression: the NS1 Protein Enhances Translation and Is Not Required for Shutoff of Host Protein Synthesis

The influenza A virus NS1 protein, a virus-encoded alpha/beta interferon (IFN-α/β) antagonist, appears to be a key regulator of protein expression in infected cells. We now show that NS1 protein expression results in enhancement of reporter gene activity from transfected plasmids. This effect appear...

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Publié dans:	J Virol
Auteurs principaux:	Salvatore, Mirella, Basler, Christopher F., Parisien, Jean-Patrick, Horvath, Curt M., Bourmakina, Svetlana, Zheng, Hongyong, Muster, Thomas, Palese, Peter, García-Sastre, Adolfo
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 2002
Sujets:	Virus-Cell Interactions
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC135795/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11773396/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.3.1206-1212.2002
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