Oxidized mitochondrial DNA released after inflammasome activation is a disease biomarker for myelodysplastic syndromes

Myelodysplastic syndromes (MDS) are heterogeneous hematopoietic stem cell malignancies that can phenotypically resemble other hematologic disorders. Thus, tools that may add to current diagnostic practices could aid in disease discrimination. Constitutive innate immune activation is a pathogenetic d...

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發表在:Blood Adv
Main Authors: Ward, Grace A., McGraw, Kathy L., Abbas-Aghababazadeh, Farnoosh, Meyer, Benjamin S., McLemore, Amy F., Vincelette, Nicole D., Lam, Nghi B., Aldrich, Amy L., Al Ali, Najla H., Padron, Eric, Pinilla-Ibarz, Javier, Masala, Erico, Santini, Valeria, Kosmider, Olivier, Fontenay, Michaela, Fenaux, Pierre, Johnson, Joseph, Fridley, Brooke L., List, Alan F.
格式: Artigo
語言:Inglês
出版: American Society of Hematology 2021
主題:
Myeloid Neoplasia
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC8095151/
https://ncbi.nlm.nih.gov/pubmed/33890980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2020003475
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