Oxidized mitochondrial DNA released after inflammasome activation is a disease biomarker for myelodysplastic syndromes

Myelodysplastic syndromes (MDS) are heterogeneous hematopoietic stem cell malignancies that can phenotypically resemble other hematologic disorders. Thus, tools that may add to current diagnostic practices could aid in disease discrimination. Constitutive innate immune activation is a pathogenetic d...

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Detalles Bibliográficos
Publicado en:Blood Adv
Autores principales: Ward, Grace A., McGraw, Kathy L., Abbas-Aghababazadeh, Farnoosh, Meyer, Benjamin S., McLemore, Amy F., Vincelette, Nicole D., Lam, Nghi B., Aldrich, Amy L., Al Ali, Najla H., Padron, Eric, Pinilla-Ibarz, Javier, Masala, Erico, Santini, Valeria, Kosmider, Olivier, Fontenay, Michaela, Fenaux, Pierre, Johnson, Joseph, Fridley, Brooke L., List, Alan F.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Hematology 2021
Materias:
Myeloid Neoplasia
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8095151/
https://ncbi.nlm.nih.gov/pubmed/33890980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2020003475
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