Oxidized mitochondrial DNA released after inflammasome activation is a disease biomarker for myelodysplastic syndromes

Myelodysplastic syndromes (MDS) are heterogeneous hematopoietic stem cell malignancies that can phenotypically resemble other hematologic disorders. Thus, tools that may add to current diagnostic practices could aid in disease discrimination. Constitutive innate immune activation is a pathogenetic d...

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Bibliographic Details
Published in:Blood Adv
Main Authors: Ward, Grace A., McGraw, Kathy L., Abbas-Aghababazadeh, Farnoosh, Meyer, Benjamin S., McLemore, Amy F., Vincelette, Nicole D., Lam, Nghi B., Aldrich, Amy L., Al Ali, Najla H., Padron, Eric, Pinilla-Ibarz, Javier, Masala, Erico, Santini, Valeria, Kosmider, Olivier, Fontenay, Michaela, Fenaux, Pierre, Johnson, Joseph, Fridley, Brooke L., List, Alan F.
Format: Artigo
Language:Inglês
Published: American Society of Hematology 2021
Subjects:
Myeloid Neoplasia
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8095151/
https://ncbi.nlm.nih.gov/pubmed/33890980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2020003475
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