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Differential Splicing of Human Adenovirus 5 E1A RNA Expressed in cis versus in trans

Human adenovirus (HAdV) is used extensively as a vector for gene delivery for a variety of purposes, including gene therapy and vaccine development. Most adenoviral vectors used for these approaches have a deletion of early region 1 (E1), which is complemented by the cell line. Most commonly, these...

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Bibliographische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Graves, Drayson, Akkerman, Nikolas, Bachus, Scott, Pelka, Peter
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8094950/
https://ncbi.nlm.nih.gov/pubmed/33361423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02081-20
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