Sequence Evaluation and Comparative Analysis of Novel Assays for Intact Proviral HIV-1 DNA

The HIV proviral reservoir is the major barrier to cure. The predominantly replication-defective proviral landscape makes the measurement of virus that is likely to cause rebound upon antiretroviral therapy (ART)-cessation challenging. To address this issue, novel assays to measure intact HIV provir...

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Udgivet i:J Virol
Main Authors: Gaebler, Christian, Falcinelli, Shane D., Stoffel, Elina, Read, Jenna, Murtagh, Ross, Oliveira, Thiago Y., Ramos, Victor, Lorenzi, Julio C. C., Kirchherr, Jennifer, James, Katherine S., Allard, Brigitte, Baker, Caroline, Kuruc, JoAnn D., Caskey, Marina, Archin, Nancie M., Siliciano, Robert F., Margolis, David M., Nussenzweig, Michel C.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2021
Fag:
Pathogenesis and Immunity
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8094944/
https://ncbi.nlm.nih.gov/pubmed/33361426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01986-20
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