Sequence Evaluation and Comparative Analysis of Novel Assays for Intact Proviral HIV-1 DNA

The HIV proviral reservoir is the major barrier to cure. The predominantly replication-defective proviral landscape makes the measurement of virus that is likely to cause rebound upon antiretroviral therapy (ART)-cessation challenging. To address this issue, novel assays to measure intact HIV provir...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Gaebler, Christian, Falcinelli, Shane D., Stoffel, Elina, Read, Jenna, Murtagh, Ross, Oliveira, Thiago Y., Ramos, Victor, Lorenzi, Julio C. C., Kirchherr, Jennifer, James, Katherine S., Allard, Brigitte, Baker, Caroline, Kuruc, JoAnn D., Caskey, Marina, Archin, Nancie M., Siliciano, Robert F., Margolis, David M., Nussenzweig, Michel C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2021
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8094944/
https://ncbi.nlm.nih.gov/pubmed/33361426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01986-20
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