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N-terminal domain of TDP43 enhances liquid-liquid phase separation of globular proteins

Liquid-liquid phase separation (LLPS) of proteins is involved in a growing number of cellular processes. Most proteins with LLPS harbor intrinsically disordered regions (IDR), which serve as a guideline to search for cellular proteins that potentially phase separate. Herein, we reveal that oligomeri...

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Detalhes bibliográficos
Publicado no:J Mol Biol
Main Authors: Carter, G. Campbell, Hsiung, Chia-Heng, Simpson, Leman, Yang, Haopeng, Zhang, Xin
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8094807/
https://ncbi.nlm.nih.gov/pubmed/33744316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2021.166948
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