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An Antibody to the Aggregated Synthetic Prion Protein Peptide (PrP106–126) Selectively Recognizes Disease‐Associated Prion Protein (PrP(Sc)) from Human Brain Specimens

Human prion diseases are characterized by the conversion of the normal host cellular prion protein (PrP(C)) into an abnormal misfolded form [disease‐associated prion protein (PrP(Sc))]. Antibodies that are capable of distinguishing between PrP(C) and PrP(Sc) may prove to be useful, not only for the...

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Dades bibliogràfiques
Publicat a:Brain Pathol
Autors principals: Jones, Michael, Wight, Darren, McLoughlin, Victoria, Norrby, Katherine, Ironside, James W., Connolly, John G., Farquhar, Christine F., MacGregor, Ian R., Head, Mark W.
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Ltd 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8094797/
https://ncbi.nlm.nih.gov/pubmed/18507665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1750-3639.2008.00181.x
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