An Antibody to the Aggregated Synthetic Prion Protein Peptide (PrP106–126) Selectively Recognizes Disease‐Associated Prion Protein (PrP(Sc)) from Human Brain Specimens

Human prion diseases are characterized by the conversion of the normal host cellular prion protein (PrP(C)) into an abnormal misfolded form [disease‐associated prion protein (PrP(Sc))]. Antibodies that are capable of distinguishing between PrP(C) and PrP(Sc) may prove to be useful, not only for the...

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Detalhes bibliográficos
Publicado no:Brain Pathol
Main Authors: Jones, Michael, Wight, Darren, McLoughlin, Victoria, Norrby, Katherine, Ironside, James W., Connolly, John G., Farquhar, Christine F., MacGregor, Ian R., Head, Mark W.
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2008
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8094797/
https://ncbi.nlm.nih.gov/pubmed/18507665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1750-3639.2008.00181.x
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