The Toxicity of the PrP106-126 Prion Peptide on Cultured Photoreceptors Correlates with the Prion Protein Distribution in the Mammalian and Human Retina

In patients affected by Creutzfeldt-Jakob disease and in animals affected by transmissible spongiform encephalopathies, retinal functions are altered, and major spongiform changes are observed in the outer plexiform layer where photoreceptors have their synaptic terminals. In the present study, the...

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Main Authors: Gong, Jie, Jellali, Abdeljelil, Forster, Valérie, Mutterer, Jérôme, Dubus, Elisabeth, Altrock, Wilko D., Sahel, José A., Rendon, Alvaro, Picaud, Serge
Format: Artigo
Language:Inglês
Published: American Society for Investigative Pathology 2007
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1829464/
https://ncbi.nlm.nih.gov/pubmed/17392170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2007.060340
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