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Multi-tissue neocortical transcriptome-wide association study implicates 8 genes across 6 genomic loci in Alzheimer’s disease

BACKGROUND: Alzheimer’s disease (AD) is an incurable neurodegenerative disease currently affecting 1.75% of the US population, with projected growth to 3.46% by 2050. Identifying common genetic variants driving differences in transcript expression that confer AD risk is necessary to elucidate AD mec...

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Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:	Genome Med
Κύριοι συγγραφείς:	Gockley, Jake, Montgomery, Kelsey S., Poehlman, William L., Wiley, Jesse C., Liu, Yue, Gerasimov, Ekaterina, Greenwood, Anna K., Sieberts, Solveig K., Wingo, Aliza P., Wingo, Thomas S., Mangravite, Lara M., Logsdon, Benjamin A.
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	BioMed Central 2021
Θέματα:	Research
Διαθέσιμο Online:	https://ncbi.nlm.nih.gov/pmc/articles/PMC8094491/ https://ncbi.nlm.nih.gov/pubmed/33947463 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-021-00890-2
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Multi-tissue neocortical transcriptome-wide association study implicates 8 genes across 6 genomic loci in Alzheimer’s disease

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