Multi-tissue neocortical transcriptome-wide association study implicates 8 genes across 6 genomic loci in Alzheimer’s disease

BACKGROUND: Alzheimer’s disease (AD) is an incurable neurodegenerative disease currently affecting 1.75% of the US population, with projected growth to 3.46% by 2050. Identifying common genetic variants driving differences in transcript expression that confer AD risk is necessary to elucidate AD mec...

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Detalhes bibliográficos
Publicado no:Genome Med
Main Authors: Gockley, Jake, Montgomery, Kelsey S., Poehlman, William L., Wiley, Jesse C., Liu, Yue, Gerasimov, Ekaterina, Greenwood, Anna K., Sieberts, Solveig K., Wingo, Aliza P., Wingo, Thomas S., Mangravite, Lara M., Logsdon, Benjamin A.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8094491/
https://ncbi.nlm.nih.gov/pubmed/33947463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-021-00890-2
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