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Role of Cytotoxic Protease Granzyme‐b in Neuronal Degeneration During Human Stroke

Infiltration of leukocytes into post‐ischemic cerebrum is a well‐described phenomenon in stroke injury. Because CD‐8(+) T‐lymphocytes secrete cytotoxic proteases, including granzyme‐b (Gra‐b) that exacerbates post‐ischemic brain damage, we investigated roles of Gra‐b in human stroke. To study the ro...

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Detalhes bibliográficos
Publicado no:Brain Pathol
Main Authors: Chaitanya, Ganta Vijay, Eeka, Prabhakar, Munker, Reinhold, Alexander, Jonathan Steven, Babu, Phanithi Prakash
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8094313/
https://ncbi.nlm.nih.gov/pubmed/20825413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1750-3639.2010.00426.x
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