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Mitochondrial Entry of Cytotoxic Proteases: A New Insight into the Granzyme B Cell Death Pathway

The mitochondria represent an integration and amplification hub for various death pathways including that mediated by granzyme B (GB), a granule enzyme expressed by cytotoxic lymphocytes. GB activates the proapoptotic B cell CLL/lymphoma 2 (Bcl-2) family member BH3-interacting domain death agonist (...

詳細記述

保存先:
書誌詳細
出版年:Oxid Med Cell Longev
第一著者: Martinvalet, Denis
フォーマット: Artigo
言語:Inglês
出版事項: Hindawi 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6556269/
https://ncbi.nlm.nih.gov/pubmed/31249651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/9165214
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