Presence of Tissue Transglutaminase in Granular Endoplasmic Reticulum is Characteristic of Melanized Neurons in Parkinson's Disease Brain

Parkinson's disease (PD) is characterized by the accumulation of α‐synuclein aggregates and degeneration of melanized neurons. The tissue transglutaminase (tTG) enzyme catalyzes molecular protein cross‐linking. In PD brain, tTG‐induced cross‐links have been identified in α‐synuclein monomers, o...

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Bibliografiske detaljer
Udgivet i:Brain Pathol
Main Authors: Wilhelmus, Micha M. M., Verhaar, Robin, Andringa, Gerda, Bol, John G. J. M., Cras, Patrick, Shan, Ling, Hoozemans, Jeroen J. M., Drukarch, Benjamin
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Publishing Ltd 2010
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Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8094245/
https://ncbi.nlm.nih.gov/pubmed/20731657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1750-3639.2010.00429.x
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