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Tissue Transglutaminase Appears in Monocytes and Macrophages but Not in Lymphocytes in White Matter Multiple Sclerosis Lesions

Leukocyte infiltration is an important pathological hallmark of multiple sclerosis (MS) and is therefore targeted by current MS therapies. The enzyme tissue transglutaminase (TG2) contributes to monocyte/macrophage migration and is present in MS lesions and could be a potential therapeutic target. W...

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Опубликовано в: :J Neuropathol Exp Neurol
Главные авторы: Chrobok, Navina L, Bol, John G J M, Wilhelmus, Micha M M, Drukarch, Benjamin, van Dam, Anne-Marie
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2019
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6524631/
https://ncbi.nlm.nih.gov/pubmed/31058279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnen/nlz030
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