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Tissue Transglutaminase Appears in Monocytes and Macrophages but Not in Lymphocytes in White Matter Multiple Sclerosis Lesions

Leukocyte infiltration is an important pathological hallmark of multiple sclerosis (MS) and is therefore targeted by current MS therapies. The enzyme tissue transglutaminase (TG2) contributes to monocyte/macrophage migration and is present in MS lesions and could be a potential therapeutic target. W...

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Detalhes bibliográficos
Publicado no:J Neuropathol Exp Neurol
Main Authors: Chrobok, Navina L, Bol, John G J M, Wilhelmus, Micha M M, Drukarch, Benjamin, van Dam, Anne-Marie
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6524631/
https://ncbi.nlm.nih.gov/pubmed/31058279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnen/nlz030
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