Characterization of Transglutaminase 2 activity inhibitors in monocytes in vitro and their effect in a mouse model for multiple sclerosis

The neurodegenerative disease multiple sclerosis (MS) is pathologically characterized by the massive influx of immune cells into the central nervous system. This contributes to demyelination and axonal damage which causes symptoms such as motor and cognitive dysfunctions. The migration of leukocytes...

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Publicado en:PLoS One
Autores principales: Chrobok, Navina L., Bol, John G. J. M., Jongenelen, Cornelis A., Brevé, John J. P., El Alaoui, Said, Wilhelmus, Micha M. M., Drukarch, Benjamin, van Dam, Anne-Marie
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2018
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5918173/
https://ncbi.nlm.nih.gov/pubmed/29689097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0196433
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