Characterization of Transglutaminase 2 activity inhibitors in monocytes in vitro and their effect in a mouse model for multiple sclerosis

The neurodegenerative disease multiple sclerosis (MS) is pathologically characterized by the massive influx of immune cells into the central nervous system. This contributes to demyelination and axonal damage which causes symptoms such as motor and cognitive dysfunctions. The migration of leukocytes...

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Vydáno v:PLoS One
Hlavní autoři: Chrobok, Navina L., Bol, John G. J. M., Jongenelen, Cornelis A., Brevé, John J. P., El Alaoui, Said, Wilhelmus, Micha M. M., Drukarch, Benjamin, van Dam, Anne-Marie
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2018
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5918173/
https://ncbi.nlm.nih.gov/pubmed/29689097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0196433
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