Presence of Tissue Transglutaminase in Granular Endoplasmic Reticulum is Characteristic of Melanized Neurons in Parkinson's Disease Brain

Parkinson's disease (PD) is characterized by the accumulation of α‐synuclein aggregates and degeneration of melanized neurons. The tissue transglutaminase (tTG) enzyme catalyzes molecular protein cross‐linking. In PD brain, tTG‐induced cross‐links have been identified in α‐synuclein monomers, o...

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Detaylı Bibliyografya
Yayımlandı:Brain Pathol
Asıl Yazarlar: Wilhelmus, Micha M. M., Verhaar, Robin, Andringa, Gerda, Bol, John G. J. M., Cras, Patrick, Shan, Ling, Hoozemans, Jeroen J. M., Drukarch, Benjamin
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Blackwell Publishing Ltd 2010
Konular:
Research Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8094245/
https://ncbi.nlm.nih.gov/pubmed/20731657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1750-3639.2010.00429.x
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