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Cytoskeletal-based mechanisms differently regulate in vivo and in vitro proplatelet formation

Platelets are produced by bone marrow megakaryocytes through cytoplasmic protrusions, named native proplatelets (nPPT), into blood vessels. Proplatelets also refer to protrusions observed in megakaryocyte culture (cultured proplatelets [cPPT]) which are morphologically different. Contrary to cPPT, t...

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Vydáno v:Haematologica
Hlavní autoři: Bornert, Alicia, Boscher, Julie, Pertuy, Fabien, Eckly, Anita, Stegner, David, Strassel, Catherine, Gachet, Christian, Lanza, François, Léon, Catherine
Médium: Artigo
Jazyk:Inglês
Vydáno: Fondazione Ferrata Storti 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8094084/
https://ncbi.nlm.nih.gov/pubmed/32327502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2019.239111
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