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Intrinsic impaired proplatelet formation and microtubule coil assembly of megakaryocytes in a mouse model of Bernard-Soulier syndrome
BACKGROUND: Giant platelets and thrombocytopenia are invariable defects in the Bernard-Soulier syndrome caused by deficiency of the GPIb-V-IX complex, a receptor for von Willebrand factor supporting platelet adhesion to the damaged arterial wall. Various properties of this receptor may be considered...
में बचाया:
मुख्य लेखकों: | , , , , , , , |
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स्वरूप: | Artigo |
भाषा: | Inglês |
प्रकाशित: |
Ferrata Storti Foundation
2009
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विषय: | |
ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2688571/ https://ncbi.nlm.nih.gov/pubmed/19377075 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2008.001032 |
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