Cytoskeletal-based mechanisms differently regulate in vivo and in vitro proplatelet formation

Platelets are produced by bone marrow megakaryocytes through cytoplasmic protrusions, named native proplatelets (nPPT), into blood vessels. Proplatelets also refer to protrusions observed in megakaryocyte culture (cultured proplatelets [cPPT]) which are morphologically different. Contrary to cPPT, t...

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Bibliographic Details
Published in:Haematologica
Main Authors: Bornert, Alicia, Boscher, Julie, Pertuy, Fabien, Eckly, Anita, Stegner, David, Strassel, Catherine, Gachet, Christian, Lanza, François, Léon, Catherine
Format: Artigo
Language:Inglês
Published: Fondazione Ferrata Storti 2020
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8094084/
https://ncbi.nlm.nih.gov/pubmed/32327502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2019.239111
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