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Cytoskeletal-based mechanisms differently regulate in vivo and in vitro proplatelet formation

Platelets are produced by bone marrow megakaryocytes through cytoplasmic protrusions, named native proplatelets (nPPT), into blood vessels. Proplatelets also refer to protrusions observed in megakaryocyte culture (cultured proplatelets [cPPT]) which are morphologically different. Contrary to cPPT, t...

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Publicado en:Haematologica
Main Authors: Bornert, Alicia, Boscher, Julie, Pertuy, Fabien, Eckly, Anita, Stegner, David, Strassel, Catherine, Gachet, Christian, Lanza, François, Léon, Catherine
Formato: Artigo
Idioma:Inglês
Publicado: Fondazione Ferrata Storti 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8094084/
https://ncbi.nlm.nih.gov/pubmed/32327502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2019.239111
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