Papaverine Exerts Neuroprotective Effect by Inhibiting NLRP3 Inflammasome Activation in an MPTP-Induced Microglial Priming Mouse Model Challenged with LPS

Microglial priming is the process of microglial proliferation and activation in response to neurodegeneration and abnormal protein accumulation. Priming makes microglia susceptible to secondary inflammatory stimuli and causes exaggerated inflammatory responses. In the present study, we established a...

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Detaylı Bibliyografya
Yayımlandı:Biomol Ther (Seoul)
Asıl Yazarlar: Leem, Yea-Hyun, Park, Jin-Sun, Park, Jung-Eun, Kim, Do-Yeon, Kim, Hee-Sun
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Korean Society of Applied Pharmacology 2021
Konular:
Original Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8094076/
https://ncbi.nlm.nih.gov/pubmed/33911050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4062/biomolther.2021.039
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