Papaverine Exerts Neuroprotective Effect by Inhibiting NLRP3 Inflammasome Activation in an MPTP-Induced Microglial Priming Mouse Model Challenged with LPS

Microglial priming is the process of microglial proliferation and activation in response to neurodegeneration and abnormal protein accumulation. Priming makes microglia susceptible to secondary inflammatory stimuli and causes exaggerated inflammatory responses. In the present study, we established a...

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Vydáno v:Biomol Ther (Seoul)
Hlavní autoři: Leem, Yea-Hyun, Park, Jin-Sun, Park, Jung-Eun, Kim, Do-Yeon, Kim, Hee-Sun
Médium: Artigo
Jazyk:Inglês
Vydáno: The Korean Society of Applied Pharmacology 2021
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8094076/
https://ncbi.nlm.nih.gov/pubmed/33911050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4062/biomolther.2021.039
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