Papaverine Exerts Neuroprotective Effect by Inhibiting NLRP3 Inflammasome Activation in an MPTP-Induced Microglial Priming Mouse Model Challenged with LPS

Microglial priming is the process of microglial proliferation and activation in response to neurodegeneration and abnormal protein accumulation. Priming makes microglia susceptible to secondary inflammatory stimuli and causes exaggerated inflammatory responses. In the present study, we established a...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Biomol Ther (Seoul)
Main Authors: Leem, Yea-Hyun, Park, Jin-Sun, Park, Jung-Eun, Kim, Do-Yeon, Kim, Hee-Sun
Format: Artigo
Jezik:Inglês
Izdano: The Korean Society of Applied Pharmacology 2021
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8094076/
https://ncbi.nlm.nih.gov/pubmed/33911050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4062/biomolther.2021.039
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