Papaverine Exerts Neuroprotective Effect by Inhibiting NLRP3 Inflammasome Activation in an MPTP-Induced Microglial Priming Mouse Model Challenged with LPS

Microglial priming is the process of microglial proliferation and activation in response to neurodegeneration and abnormal protein accumulation. Priming makes microglia susceptible to secondary inflammatory stimuli and causes exaggerated inflammatory responses. In the present study, we established a...

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Foilsithe in:Biomol Ther (Seoul)
Main Authors: Leem, Yea-Hyun, Park, Jin-Sun, Park, Jung-Eun, Kim, Do-Yeon, Kim, Hee-Sun
Formáid: Artigo
Teanga:Inglês
Foilsithe: The Korean Society of Applied Pharmacology 2021
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Original Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8094076/
https://ncbi.nlm.nih.gov/pubmed/33911050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4062/biomolther.2021.039
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