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Bmi1 regulate tooth and mandible development by inhibiting p16 signal pathway

To determine whether the deletion of p16 can correct tooth and mandible growth retardation caused by Bmi1 deficiency, we compared the tooth and mandible phenotypes of homozygous p16‐deficient (p16(−/−)) mice, homozygous Bmi1‐deficient (Bmi1(−/−)) mice, double homozygous Bmi1 and p16‐deficient (Bmi1(...

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Pubblicato in:J Cell Mol Med
Autori principali: Yin, Ying, Zhou, Nan, Zhang, Hui, Dai, Xiuliang, Lv, Xianhui, Chen, Ning, Miao, Dengshun, Hu, Qingang
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8093977/
https://ncbi.nlm.nih.gov/pubmed/33745198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.16468
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