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Bmi1 regulate tooth and mandible development by inhibiting p16 signal pathway

To determine whether the deletion of p16 can correct tooth and mandible growth retardation caused by Bmi1 deficiency, we compared the tooth and mandible phenotypes of homozygous p16‐deficient (p16(−/−)) mice, homozygous Bmi1‐deficient (Bmi1(−/−)) mice, double homozygous Bmi1 and p16‐deficient (Bmi1(...

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Dades bibliogràfiques
Publicat a:J Cell Mol Med
Autors principals: Yin, Ying, Zhou, Nan, Zhang, Hui, Dai, Xiuliang, Lv, Xianhui, Chen, Ning, Miao, Dengshun, Hu, Qingang
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8093977/
https://ncbi.nlm.nih.gov/pubmed/33745198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.16468
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