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Lin28a ameliorates glucotoxicity-induced β-cell dysfunction and apoptosis

An excessive and prolonged increase in glucose levels causes β-cell dysregulation, which is accompanied by impaired insulin synthesis and secretion, a condition known as glucotoxicity. Although it is known that both Lin28a and Lin28b regulate glucose metabolism, other molecular mechanisms that may p...

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Foilsithe in:BMB Rep
Main Authors: Hwang, Yeo Jin, Jung, Gwon-Soo, Jeon, WonBae, Lee, Kyeong-Min
Formáid: Artigo
Teanga:Inglês
Foilsithe: Korean Society for Biochemistry and Molecular Biology 2021
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Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8093937/
https://ncbi.nlm.nih.gov/pubmed/33691905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5483/BMBRep.2021.54.4.255
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