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Advances in Genome Editing and Application to the Generation of Genetically Modified Rat Models

The rat has been extensively used as a small animal model. Many genetically engineered rat models have emerged in the last two decades, and the advent of gene-specific nucleases has accelerated their generation in recent years. This review covers the techniques and advances used to generate genetica...

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Detalhes bibliográficos
Publicado no:Front Genet
Main Authors: Chenouard, Vanessa, Remy, Séverine, Tesson, Laurent, Ménoret, Séverine, Ouisse, Laure-Hélène, Cherifi, Yacine, Anegon, Ignacio
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8093876/
https://ncbi.nlm.nih.gov/pubmed/33959146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2021.615491
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