Anti-Hyperuricemic and Nephroprotective Effects of Dihydroberberine in Potassium Oxonate- and Hypoxanthine-Induced Hyperuricemic Mice

Phellodendri Chinese Cortex has long been used to treat hyperuricemia and gout. Berberine (BBR), its characteristic ingredient, has also been shown to be effective in alleviating monosodium urate crystals-triggered gout inflammation in vitro and in vivo. Dihydroberberine (DHB) is a hydrogenated deri...

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Bibliographic Details
Published in:Front Pharmacol
Main Authors: Xu, Lieqiang, Lin, Guoshu, Yu, Qiuxia, Li, Qiaoping, Mai, Liting, Cheng, Juanjuan, Xie, Jianhui, Liu, Yuhong, Su, Ziren, Li, Yucui
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2021
Subjects:
Pharmacology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8093860/
https://ncbi.nlm.nih.gov/pubmed/33959014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.645879
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