Anti-Hyperuricemic and Nephroprotective Effects of Dihydroberberine in Potassium Oxonate- and Hypoxanthine-Induced Hyperuricemic Mice

Phellodendri Chinese Cortex has long been used to treat hyperuricemia and gout. Berberine (BBR), its characteristic ingredient, has also been shown to be effective in alleviating monosodium urate crystals-triggered gout inflammation in vitro and in vivo. Dihydroberberine (DHB) is a hydrogenated deri...

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Publicado en:Front Pharmacol
Autores principales: Xu, Lieqiang, Lin, Guoshu, Yu, Qiuxia, Li, Qiaoping, Mai, Liting, Cheng, Juanjuan, Xie, Jianhui, Liu, Yuhong, Su, Ziren, Li, Yucui
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8093860/
https://ncbi.nlm.nih.gov/pubmed/33959014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.645879
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