Anti-Hyperuricemic and Nephroprotective Effects of Dihydroberberine in Potassium Oxonate- and Hypoxanthine-Induced Hyperuricemic Mice

Phellodendri Chinese Cortex has long been used to treat hyperuricemia and gout. Berberine (BBR), its characteristic ingredient, has also been shown to be effective in alleviating monosodium urate crystals-triggered gout inflammation in vitro and in vivo. Dihydroberberine (DHB) is a hydrogenated deri...

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Vydáno v:Front Pharmacol
Hlavní autoři: Xu, Lieqiang, Lin, Guoshu, Yu, Qiuxia, Li, Qiaoping, Mai, Liting, Cheng, Juanjuan, Xie, Jianhui, Liu, Yuhong, Su, Ziren, Li, Yucui
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2021
Témata:
Pharmacology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8093860/
https://ncbi.nlm.nih.gov/pubmed/33959014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.645879
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