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Cyclin G2, a novel target of sulindac to inhibit cell cycle progression in colorectal cancer

Sulindac has shown significant clinical benefit in preventing colorectal cancer progression, but its mechanism of action has not been fully elucidated. We have found that sulindac sulfide (SS) is able to inhibit cell cycle progression in human colorectal cancer cells, particularly through G1 arrest....

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Genes Dis
Egile Nagusiak: Zhao, Hongyou, Yi, Bin, Liang, Zhipin, Phillips, Ches’Nique, Lin, Hui-Yi, Riker, Adam I., Xi, Yaguang
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Chongqing Medical University 2020
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC8093647/
https://ncbi.nlm.nih.gov/pubmed/33997179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gendis.2020.11.006
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