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Sulindac modulates the response of proficient MMR colorectal cancer to anti-PD-L1 immunotherapy

Immune checkpoint inhibitors (ICIs) therapy has been widely used to treat different human cancers, particularly advanced solid tumors. However, clinical studies have reported that ICI immunotherapy benefits only ~15% of colorectal cancer (CRC) patients, specifically those with tumors characterized b...

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Detalhes bibliográficos
Publicado no:Mol Cancer Ther
Main Authors: Yi, Bin, Cheng, Hao, Wyczechowska, Dorota, Yu, Qingzhao, Li, Li, Ochoa, Augusto C., Riker, Adam I., Xi, Yaguang
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8295201/
https://ncbi.nlm.nih.gov/pubmed/33879557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-20-0934
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