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Cyclin G2, a novel target of sulindac to inhibit cell cycle progression in colorectal cancer

Sulindac has shown significant clinical benefit in preventing colorectal cancer progression, but its mechanism of action has not been fully elucidated. We have found that sulindac sulfide (SS) is able to inhibit cell cycle progression in human colorectal cancer cells, particularly through G1 arrest....

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Detalhes bibliográficos
Publicado no:Genes Dis
Main Authors: Zhao, Hongyou, Yi, Bin, Liang, Zhipin, Phillips, Ches’Nique, Lin, Hui-Yi, Riker, Adam I., Xi, Yaguang
Formato: Artigo
Idioma:Inglês
Publicado em: Chongqing Medical University 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8093647/
https://ncbi.nlm.nih.gov/pubmed/33997179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gendis.2020.11.006
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